Cefiget Syrup Cefixime Uses Side-Effects Dose In Urdu

Composition

1. CEFIGET Powder for Oral Suspension 100mg/5mL
Each 5mL of reconstituted suspension contains:
Cefixime trihydrate equivalent to Cefixime USP.…100mg
2. CEFIGET DS Powder for Oral Suspension 200mg/5mL
Each 5mL of reconstituted suspension contains:
Cefixime trihydrate equivalent to Cefixime USP.…200mg

 

THERAPEUTIC indications :

Cefixime (Cefixime) is recommended to treat the following infections that are caused by

susceptible strains identified microorganisms: – Uncomplicated urinary tract infections Otitis media Pharyngitis and tonsillitis acute exacerbations and acute bronchitis of chronic bronchitis gonorrhea (cervical/urethral)

Dosage and administration :

Children and adults over 10 years: The recommended dose for adults of

CEFIGET (Cefixime) is 200- 400 mg daily based on the severity of the infection. It can be administered either in an individual dose or in two doses. Gonococcal infections that are not complicated: To treat uncomplicated gonococcal infections of the cervical or urethral region, a single oral dose of up to 400mg is suggested.

Children are advised to take 8 mg/kg/day in the suspension. It can be given in a single dose daily or in two doses divided at 4 mg/kg for 12 hours with the exception of urinary tract infections in which a single dose per day must be administered. As a general guideline to prescribe for children, the following doses are for daily use in terms of volume of oral suspension. Read the entire content before using it. This insert is regularly modified from time to time. Made by Opal Laboratories (Pvt.) Ltd., LC-41, L.I.T.E., Landhi, Karachi, Pakistan. For: recommended 6 months up one year 3.75mL per day.

Children from 1-4 years old:

5mL daily for children 5-10 years: 10mL per day Children who weigh over 50 kilograms (or older than 10 years) must be treated using the dose for adults recommended (200 up to 400 mg per day depending on the severity of the infection). Otitis Media: Otitis media is best treated using suspension. Treatment Duration The typical course of treatment lasts 7 days. The treatment can continue for up to 14 days when needed.

When treating infections caused by S. Pyogenes the therapeutic dose of CEFIGET (Cefixime) must be administered for a minimum of 10 days. Special groups Renal Insufficiency (Cefixime) is a treatment option when there is impairment of renal function. A normal dose and schedule could be administered to patients who have creatinine clearances of 20mL/min and higher. If the creatinine clearances are less than 20mL/min it is advised that a dose of up to 200 mg every day is not exceeded.

Cefiget Syrup Cefixime Uses Side-Effects Dose In Urdu

The dosage

The dosage and the regimen for patients kept on chronic ambulatory dialysis or hemodialysis ought to be based on the same guidelines as for patients who have clearances for creatinine lower than 20mL/min. Instructions for making oral Suspension Then, fill the previously boiling and chilled water to the marking on the bottle, then shake vigorously. The suspension after reconstitution can be stored for up to 14 days at room temperature or even in the refrigerator, without the loss of any effectiveness. Securely seal the container. Shake well before use. Recycle any leftover portion at the end of 14 days.

Cefiget Syrup SIDE-EFECTS

Cefixime is generally well-tolerated and any side effects are generally short-lived.

Gastrointestinal disturbance:

  • Diarrhea (if severe diarrhea occurs, cefixime should be discontinued),
  • changes in the color of stool,
  • nausea,
  • abdominal pain,
  • dyspepsia,
  • vomiting,
  • and flatulence has been reported.
  • Pseudomembranous colitis has also been reported.
  • Central nervous system disturbance:
  • Headache,
  • dizziness,
  • seizures.
  • Hepatic Conditions:
  • Transientrises of liver transaminases, alkaline phosphatase, and jaundice are also possible.
  • Other:
  • Hypersensitivity reactions that generally subside when discontinuing therapy; occasionally irreversible hematological disorders; elevation levels of amylase serum. Prothrombin-related time increases have been observed in a few patients. Other reactions that could be a result include vaginitis and genital pruritis.

Cefiget Syrup CONTRAINDICATIONS

Cefixime is not recommended for those who have hypersensitivity to any ingredient in this medication. Patients with a history of an allergy to the group of cephalosporin of antibiotics. For children under six months of age as the effectiveness and safety of cefixime in these patients haven’t been confirmed. Precautions – Cephalosporins are to be administered with caution to patients who are penicillin sensitive since there is evidence of a partial cross-allergenicity between penicillins and the cephalosporins. Cefixime – Cefixime is to be used cautiously in patients who have severely impaired renal function.

The use of wide-spectrum antibiotics can alter the colon’s normal flora and can lead to the growth of Clostridia. Pseudomembranous Colitis is a result of the use of broad-spectrum antibiotics (including macrolides semi-synthetic penicillins and cephalosporins) and it is essential to be aware of its presence for patients who experience diarrhea as a result of the treatment with antibiotics. The symptoms of pseudomembranous colitis can occur either during or following treatment with antibiotics. Broad-spectrum antibiotics, such as cefixime are recommended with caution for patients with a history of digestive disease, especially colitis. Don’t use cefixime in the treatment of S. aureus because the staphylococcus strain is intolerant to cefixime. Pregnancy There aren’t any sufficient and well-controlled studies on pregnant women.

Cefiget Syrup USE IN PREGNANCY

Cefixime is not taken during pregnancy unless it is deemed vital by the doctor. Nursing mothers, It isn’t established whether cefixime can be excreted in human milk. It is recommended to consider the temporary cessation of nursing while taking this medication. Drug Interactions with Anticoagulants It is recommended to exercise caution for patients taking anticoagulants in conjunction with cefixime because cefixime could increase the prothrombin duration.

Carbamazepine:

Increased levels of carbamazepine have been reported, when cefixime is given concurrently. Drug monitoring could assist in detecting changes in plasma levels of carbamazepine. Lab/Drug Interactions – A false positive reaction for ketones found in urine can occur when using tests using nitroprusside, but not when that use nitroferricyanide. A false-positive reaction to glucose in the urine can occur using Benedict’s or Fehling’s solution or using copper sulfate test tablets, however, not with tests that are based on the enzymatic reaction of glucose oxidase. The false positive of the Coombs test is documented in the course of treatment with cephalosporin antibiotics. Therefore, it must be noted that the positive Coombs test could be due to the medication.

 

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